They used mice, because they are good for early tries. The researchers had 9 bacterias and only 1 was successful. Experiments in mice are cheaper and have less ethical problems than experiments in humans. (Hey! They even injected the cancer cells in mice and waited a week until it grow. Nobody will approve something like that in humans.)
The title claims that the tumos were eradicated. The title hides that it was a small tumor they injected in the mice and more importantly that it disappeared for two weeks until the experiment ended. It's difficult to guess if it will be useful for humans with bigger tumors because they are harder to detect, and it would work for a interesting enough period like 5 years.
There is also and old comment by octaane https://news.ycombinator.com/item?id=46308732 I'll quote it partially:
> Several things trigger my bullshit meter. Quote:
>> "This dramatically surpasses the therapeutic efficacy of current standard treatments, including immune checkpoint inhibitors (anti-PD-L1 antibody) and liposomal doxorubicin (chemotherapy agents)"
> PD-L1 monoclonal antibodies are only effective against cancers that are PD-L1 positive. [...] Many tumor types are not PD-l1 positive.
> Doxy is an ancient SOC chemo.
> [...]
More like, what's a mouse gonna do about it?
https://www.imdb.com/title/tt0104839/?ref_=fn_t_1
In it, Connery finds what looks to be a rare natural cure to all cancer in the Rain Forest (spoiler: not a frog, but equally as weird), and is literally battling the nearby deforesting and bulldozers. For a Sean Connery movie it was bizarre (As a young teen, I saw it in the theaters.. quite a bit less action than a 007 movie but good drama and dramatic Sean Connery acting).
Connery definitely starred in even weirder movies. Have you seen Zardoz?
https://www.imdb.com/title/tt0070948/
https://m.media-amazon.com/images/M/MV5BNmI2NjI2OWYtMzU5NS00...
Buddy, if you're trying to tell me it's weirder than Darby O'Gill and the Little People, I am going to need more than Sir Connery in a ponytail.
Check out Zardoz: Connery with a ponytail, a pistol in hand, wearing thigh-high boots and a mankini.
And a giant flying stone head that vomits guns.
I am not joking.
Ewingella Americana itself is a quite common bacterial species, but it seems that the effective strain is the frog-derived and cultivated one. So don't go injecting yourself with a random E. Americana.
Full article: https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2...
EDIT: we did revert about 50% of the lawn to native wetland/prairie and we aim to raise that number over time.
One theory of where posts like this come from: https://www.pnas.org/doi/10.1073/pnas.2527316123
Definitely changing, I'm not so sure about destroying. Your house displaced an ecosystem so you could live there but I bet in your ethical system that's fine right? What a surprise
"putting power solely in the hands of the wealthiest."
Do you think it is? Then let some of the wealthiest try to obtain a permit in downtown SF for a mere block of flats, the likes of which used to be built by the thousands 100 years ago. If it takes less than a decade, I would be surprised.
There is a lot of power outside the private sector. Every environmental or political group that sues any project does, in fact, wield a lot of power of the "veto" variety, which used to be prerogative of kings.
And far better to be hiding, than watching and playing a fiddle from atop some convenient high wall. Or plotting how to destroy your fellow alpha arsonists next.
There are people who fervently believe that the world's problems are caused by something like international Jewry or lack of sufficient religiosity or existence of democracy. I fervently hope that they don't get to succeed in their solutions.
Backwards logic. If they're fond of it then they're the people to be arguing against, no?
As a child, I experienced the reality of "socialism", where every word used by the ruling elites meant something very different from what it was claimed to mean.
Unfortunately, already for more than a quarter of century USA and most "capitalistic" countries every year become more and more alike to the former socialist countries, from all points of view, like great wealth inequality, markets dominated by quasi-monopolies, non-existent political opposition, mass surveillance of the population, confusing propaganda in all mass-media, less and less chances to afford to truly be the owner of many kinds of things, like houses, cars or computers. If your car or your computer or your smartphone or your TV set do whatever their vendor or the government want, instead of doing what you want, then obviously you are not their owner.
yeah well that's because the execution matters and turns out when you give people power to choose who gets what, they abuse it. go figure.
But surely there’s a more sane option than under regulated capitalism with a problematic wealth distribution and fucked up incentives that encourage short term profit at the expense of society, environment and all else?
Because, per the article, the environmental disasters under "Socialist Russia" seem to match many of the ones in "Capitalist America". The thing in common between the two seems to be rich oligarchs controlling government, and leveraging their power to extract profits, with little regard given to the proles or the environment.
Crazy how much the supposedly "pro-capitalist" right wing mirrors the supposedly "Socialist Russia" sometimes.
Yeah, socialism was abandoned precisely because capitalism was better. By the 1980s, residents of Central Europe could quite clearly compare and saw that their western neighbours were richer, healthier and enjoyed cleaner air and water than those of the "Camp of Progress".
Market economy + democracy beats top-down enforced utopian intellectual projects like a Marxist-Leninist state by a difference of a league.
We tried that on our own people so that you don't have to.
nothing other than the prosperity that capitalism generates is inherently bad for the environment. yeah if you pull people out of poverty their carbon footprint will probably increase. but the alternative is them living in poverty and starving under a communist system (like always)
the amount of goods and services capitalism has generated has saved so many lives. we have huge amounts of excess food we send across the world.
Rather than blaming "capitalism" as a whole, I would more put the blame on our ability to ignore negative externalities when pricing things in. That occurs just as much in any other economic system.
Because we're triggering mass extinction events in the name of improving things, that's why.
While we are at it: whats with the antiquated parlance? Are we playing DnD right now?
Also who thinks -- "hmm we've found a new random bacteria --- let's give a bunch of tumors to mice and then IV inject this random thing into them!"?
There must have been something about the microbe that gave them a hint. Maybe it's in the cited original article and was left out of the blog post.
> happily
I think you answered your own question really, a lot of animals just enjoy eating them (humans included!)
Curing cancer in a mouse model is not at all uncommon in new therapies. Mouse models like this are vastly easier to treat than real world cancer for a bunch of reasons. Fully curing mice is the baseline for a treatment to even be considered for further evaluation. And even then very few therapies end up succeeding in humans - low single digit percent.
So yes, another possible treatment. But not at all a breakthrough.
Edit: Ignore me, I'm sleepy and can't read, lol
They get all the good medical breakthroughs.
Vs. there's a whole lotta of money to be made in mouse medicine.
Symbolic, perhaps?
Given that many cancer sufferers are immunocompromised, this isn't necessarily a silver bullet, although it is an interesting result.
Likely too late for a particular person in my life, but hopefully not too late for others.
Seriously though, we are living in an era where the more the science broadens its horizons, the more it just looks like plain ol' witchcraft.
I'm hoping there'll be some uses for figs we haven't thought of, next ..
https://radiolab.org/podcast/best-medicine
They followed a 1100 year old medicine recipe and found the resulting salve was effective against MRSA in their test.
https://pdfs.semanticscholar.org/06ab/f83d30ec00bb902bb1aa37...
