Cancer vaccine for Yash, he's diagnosed with stage IV pancreatic cancer(github.com)

65 pointsby AsDivyansh6 hours ago7 comments

x1798DE33 minutes ago
He was diagnosed with stage IV pancreatic cancer in January 2025 and he is still alive? Does that mean the vaccine worked? I thought that was a 3-6 month prognosis kind of deal.
I do hope it works out.
AsDivyansh5 hours ago
Complete story here: https://rnafoundry.com/yash/
polotics3 hours ago
Ok so digging into this: "We expect most projects to cost around $300,000 (USD) and take 8-10 weeks".
That's not quite democratized, but a first-world rush could well happen. I wonder how much costs can be brought down by automation.
- solyin2 hours ago
  There's millionaires and there's billionaires'. There's "is this even possible" in the first place. Rich people get to fund treatments for themselves but I can't wait till it's $30 and available at the store down the street.
syntaxing2 hours ago
Super cool, I’m more curious how this is manufactured. Would love to learn more about that
sbseitz4 hours ago
This better be the future! I love it.
hn_submit4 hours ago
I'm much rather see them repair damaged DNA in cancer cells to cure it.
- HedonicEscal8r2 hours ago
  DNA in cancer cells is often scrambled beyond recognition, not just "damaged." And even magically replacing it with normal DNA may not solve your problem.
aeve8905 hours ago
An open development of a custom cancer vaccine? I had no idea this was a thing.
- AsDivyansh5 hours ago
  I am glad, someone is trying. Hope it works out! Someone did similar in the past: https://www.the-scientist.com/chatgpt-and-alphafold-help-des...
  - HedonicEscal8r2 hours ago
    I wrote an article about Rosie here, back when this first came out: https://hedonicescalator.substack.com/p/did-paul-conyngham-r...
    This technology is in clinical trials, but people who need it now don't have years to wait for it. There's a lot of work to be done in engineering a legal landscape that allows people to access experimental treatments at costs as low as we can manage, without exposing manufacturers to damaging liability. I recommend this article about Jake Stillman's experience participating in clinical trials for terminal cancer (https://bessstillman.substack.com/p/please-be-dying-but-not-...) and this article by Ruxandra Teslo about bureaucratic bottlenecks in medical research (https://www.persuasion.community/p/medical-research-is-hopel...).