We know we don't get to see the bio side of the top models. They're out there solving hard maths problems etc but a query with the word 'microbes' in it often kicks you back to a smaller model automatically.
Are the bleeding edge models finding something scary enough that can be done with synthetic DNA that it needs to be restricted asap?
This is old stuff, being implemented and getting lots of news.
Usually the synthesis of oligonuclotides is done with phosphoramidite chemistry [0]. So tell us more about those enzymes to make DNA molecules from scratch.
[0] https://www.twistbioscience.com/blog/science/simple-guide-ph...
This works in aqueous solution under mild conditions and enables synthesis of much longer oligos (~1,000 bases), which can subsequently be assembled into 50 kbp constructs.
Not sure about that inkjet printer analogy.
Unless we are talking about really long oligos (which is harder and $$$), you’ll need some post-synthesis enzymatic work to get your full strand.
I guess it's not a bad idea to put basic hurdles in place but it would be a serious mistake to see this as any sort of comprehensive preventative. DNA just isn't difficult to manipulate.
This reeks of the Longtermists getting their influence into government. They were doing an entire round on YouTube about a year ago.
Seems like this has little to do with deterring terrorism then, considering the assumption that a terrorist may not be a US government funded scientist.
But yes, this is stupid. No one who is inclined to build a biological WMD is going to be more than mildly inconvenienced by supply restrictions. DNA isn't plutonium.
I am detecting a bit of frustration here.
(Also, my comment is great, because I wrote something instead of nothing.)
Carry on, everything is apparently fine.