I assume the article isn't too different to [1] It presents an interesting concept of looking for specific changes and reintroducing those they suspect might be beneficial to the immune systems proper function.

I feel that they're overlooking medical conditions like like gastro paralysis and gastroparesis which some sources link or associate a proportion of cases with spinal injuries. Gastroparesis when severe can cause periods of dehydration which greatly affects the every day function of the lower gut and gut's normal microbiome.

Looking for more information I noted [2] which goes into some depth in regard to Fecal Microbiota Transplantation (FMT) in mice, while they note large difference to human digestion track, it offers clues for future efforts to treat those who have gut related issues due to spinal damage or wear and tear associated with getting older.

[1] https://news.osu.edu/spinal-cord-injury-reshapes-gut-microbe...

[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC12745463/ (Dec 2025)