Efficacy of Ibuprofen versus Acetaminophen for Acute Fever in Febrile Children(link.springer.com)
5 pointsby XzetaU83 hours ago3 comments
  • marmarama2 hours ago
    The weaker antipyretic effect of paracetamol/acetaminophen compared with ibuprofen has been known about for decades in adult studies.

    It would have been surprising to obtain a different result in children.

  • pmdulaney3 hours ago
    I had always read that acetaminophen/Tylenol was the gold standard for fever reduction, so this result (ibuprofen/Advil marginally better than acetaminophen/Tylenol) is mildly surprising to me.
    • srean2 hours ago
      Paracetamol is in general safer than ibuprofen unless you are allergic to paracetamol, in which case the result can be quite gruesome and bloody.

      Paracetamol is not a blood thinner. There are not many OTC painkillers that are not blood thinners.

  • manvillej3 hours ago
    As someone who has been around a sick child, I’ll take the statistically significant temperature reduction at 4h of ibuprofen.