Creatine improves muscle mass and cognitive function even without exercise(www.psypost.org)
17 pointsby geox9 hours ago3 comments
  • upheaval72768 hours ago
    this article is garbage, likely just written by AI without any proofreading. so many things in the article are wrong after reading the study a bit. for example, study says 73 people, article says 64. Article says only part of the participants were in a caloric deficit. Study says "All participants followed a diet plan aligned with the American Heart Association's macronutrient recommendations (55% carbohydrate, 15% protein, 30% fat) to induce a modest energy deficit of approximately 300–500 kcal/day.". etc, etc

    skip the article, read the study at https://www.tandfonline.com/doi/full/10.1080/15502783.2026.2...

    • wnissen7 hours ago
      You may be right about the article but 64 is the correct number:

          64 completed week 12 and were included in the repeated-measures analysis.
    • nonsensical_8 hours ago
      You will consume slop on HN and you will be happy.
  • comrade12347 hours ago
    Don't you normally have about a kilo (or 500g?) excess as backup energy stored in your muscles and liver(?)? Why would taking a few dozen grams help?
  • 151558 hours ago
    The question is: does it increase muscle nuclei or just water volume?
    • upheaval72768 hours ago
      good question, and DXA won't tell you the answer there (they used DXA in the study) So not an especially convincing study in that case, since creatine leads to increased water retention.
    • IncreasePosts8 hours ago
      (A meta analysis)

      https://pmc.ncbi.nlm.nih.gov/articles/PMC5679696/?utm_source...

      > For example, over 8 weeks of resistance training in young men, creatine supplementation resulted in a faster increase in satellite cell number, myonuclei per muscle fiber, and muscle fiber size.

      • 151555 hours ago
        > resistance training

        Yes, but what about sedentary individuals?

      • upheaval72768 hours ago
        that's an entirely different study with different goals
        • IncreasePosts8 hours ago
          The question was asked whether creatine increases muscle nuclei or just water volume, and I provided a study (well, a meta-study which is referring to a specific study) which showed that creatine supplementation increased the muscle nuclei compared to no supplementation. The specific study referred to is titled "Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training"
          • upheaval72767 hours ago
            the interesting claim about the study in the OP is that creatine increases muscle mass in non-trained/sedentary individuals. i haven't seen that claim previously (backed by a study) and took the question from user "15155" to be about that specifically. the claim that it increases muscle mass when combined with resistance training seems to be long-settled though