17 pointsby marc__16 hours ago6 comments
  • root-parent5 hours ago
    There is nothing to see here yet other than their stock popped 50%. Based on unpublished data...

    - The initial 49% number comes from a very small phase 2 trial that had only 157 patients. And their original p-value was 0.053

    - This phase 3 news so far is nothing more than a press release. They have not published hazard ratio, or confidence interval, their event counts or survival curves.

    - They met the endppoint as used in the press release means nothing, until they publish the actual 3 data, so my money is at the end this will be a kind of marginal effect that researchers will struggle to reproduce for years

    This is the type of study that will take 3 to 4 years to validate or dismiss, in the meanwhile stock is up 50%....

  • rvz5 hours ago
    The news here is significant and this took decades of studies and research to validate this.

    Well done to Merck and Moderna.

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  • johnbarron5 hours ago
    [dead]
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