173 pointsby xtreak292 hours ago29 comments
  • cjbarberan hour ago
    From Jeff's twitter post:

    > Our general approach is to automate the experimental loop. We think this approach is broadly applicable across many different fields of science and engineering. We’ll initially focus on ML research and engineering, but believe the approach can help with important subproblems in nearly every one of the fourteen <at>NAE Grand Challenge problems. We think doing this well requires strong expertise in machine learning as well as large-scale systems.

    See also: https://www.nae.edu/20782/grand-challenges-project

    Those 14 are:

    NAE Grand Challenges for Engineering

    1. Make Solar Energy Economical

    2. Provide Energy from Fusion

    3. Develop Carbon Sequestration Methods

    4. Manage the Nitrogen Cycle

    5. Provide Access to Clean Water

    6. Restore and Improve Urban Infrastructure

    7. Advance Health Informatics

    8. Engineer Better Medicines

    9. Reverse Engineer the Brain

    10. Prevent Nuclear Terror

    11. Secure Cyberspace

    12. Enhance Virtual Reality

    13. Advance Personalized Learning

    14. Engineer the Tools of Scientific Discovery

    • LogicFailsMe14 minutes ago
      Sandbox 2.0

      But also, solar power is already economical.

    • la64710a few seconds ago
      Please add fixing neuro issues like autism add etc on the list. It creates a huge burden on families.
    • tcp_handshaker36 minutes ago
      Acquisition back by Google in 3 years, with nothing to show for it. VCs will make a ton.
      • ex1fm3ta6 minutes ago
        Sometimes you got to find a way to buy the silence of your top employee, to prevent them from going to the competition. This "start-up" is shallow as hell
      • tgma33 minutes ago
        and... the VC is Google.

        Gotta compensate them somehow.

      • DataDaoDe33 minutes ago
        My thoughts exactly
      • dude25071127 minutes ago
        For all we know, they could have been successfully working on "10. Prevent Nuclear Terror" for the last 80+ years.
  • drivebyhooting13 minutes ago
    How do you automate experimentation?

    Doubtlessly, AI can iterate at superhuman speeds in the domains of thought and design: Software, mathematical proofs, literature search.

    But in the realm of experiment? Alas it is the lack of a body that constrains it.

    Rather than transcendence what AI requires is immanence. In the human flesh may we find the godhead living among men. Let the laboratories, warehouses, and factories fill with the sound of its labor, as it builds a wall with a million hands that are not its own.

    “Give me your tired, your poor, Your huddled masses yearning to breathe free, The wretched refuse of your teeming shore. Send these, the homeless, tempest-tost to me, I lift my lamp beside the golden door!”

    • mbonneta minute ago
      > transcendence

      > immanence

      somebody has been studying Christian theology!

    • moelf9 minutes ago
      would love to see how AI can automate the construction of the next high energy particle collider
      • scrlka few seconds ago
        "You're absolutely right! I shouldn't have pushed the anti-mass spectrometer to 105%, which triggered a resonance cascade. This was a major oversight on my part."
  • pelagicAustral22 minutes ago
    Really seems to embrace the "Making the world a better place by <<extremely convoluted, highly technical, jargon loaded mission statement>>"
  • ramon15631 minutes ago
    "Our mission is straightforward" continued by the most complex sentence on that page. Wondering what the definition of straightforward is now
    • pphysch24 minutes ago
      Right. What about the scientific hardware (instruments, sensors, robotics)? Partnerships with existing research institutions? Dealing with restricted data?

      Modernizing science is a lot more complicated than just optimizing the inner experimental loop, but their hiring page implies it's a pure ML lab focused mainly on model development.

  • arjiean hour ago
    This is very cool. It might be a new scientific revolution to have computer-driven discovery. So often we find things that are "this could have been done 20 years ago" and with an indefatigable searcher perhaps we'll close all those things. Though it does remind me of that Ted Chiang (I think) story where humans and superhumans coexist and all the science of the former is meta-studies of the work of the latter.
    • PaulDavisThe1st36 minutes ago
      > It might be a new scientific revolution to have computer-driven discovery.

      And ... it might not.

      • arjie36 minutes ago
        True, nothing might be anything. But I'm an optimist :)
  • claiir4 minutes ago
    The job req has "Recursive Self-Improvement" as one of the "area of expertise" checkboxes lol
  • GodelNumbering13 minutes ago
    This is one of the interesting aspects the 'AI job loss' community doesn't account for. As the technology unlocks things, more startups are created. And even at a lower nominal work-to-engineer ratio, overall demand for talent still goes up. Ultimately, we are not a single group trying to achieve a common outcome, we are a collection of many groups trying to compete against each other.
  • 5 minutes ago
    undefined
  • claiir32 minutes ago
    The site itself is really leaning into the “made with Fable” aesthetic
    • pelagicAustral26 minutes ago
      Why are people so sour about this?? I can read the site easily, its clear, performs well on mobile, what else do you want? Why is so offensive to people that models trained on tailwind or whatever?
      • swalsh23 minutes ago
        If this was a design firm, it might matter. But this is mostly a hiring ad for engineers, and a landing page for VC. I'd judge them more if they actually put effort into it.
      • jonas2119 minutes ago
        And on top of that, the HTML is simple and readable too. I wish more sites were like this.
      • make323 minutes ago
        it's just a low effort snark comment, don't offer think it
      • slopinthebag20 minutes ago
        Because it’s lame and aesthetics matter.
    • swalsh24 minutes ago
      let me rephrase that:

      "The site itself demonstrates the team is spending their money in the places that matter, and using quick solutions for the stuff they need but isn't mission critical"

    • IshKebab20 minutes ago
      At least it isn't dark purple.
  • stephantulan hour ago
    I’ve always felt that the idea that science is bottlenecked and therefore needs more automation only works for a very narrow definition of what science is, and entails a very specific view on what it should be.
    • hobofanan hour ago
      > only works for a very narrow definition of what science is

      And so does academia. It's just that instead of AI and robotics, PhD students are thrown onto problems that are in large parts slightly tweaked reconfigurations of similar experiments.

      Especially in chemistry, biochemistry, material sciences there is a large space of discoveries that are barely "novel" in an intellectually stimulating way, but still highly valuable that can be explored orders of magnitudes faster than is currently the case.

      • stephantul26 minutes ago
        That is true, I’ve seen people do biochemistry and geology work, and it did look very mind-numbing.

        Then again, gassing rats and taking biopsies is not something you can do with AI.

      • porridgeraisin29 minutes ago
        Yep. A communications professor where I did my MS says a 200usd/mo claude sub (which ant gives for free) does as much work as 5 grad students. It's mostly like you said, trying out new ideas rapidly.
    • tcp_handshaker37 minutes ago
      Lets keep your comment out of the VC pitch deck shall we?
    • an hour ago
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  • danielmarkbruce7 minutes ago
    Automating ML/AI research seems completely tractable. Most of the other claims seem much less doable.
  • 17 minutes ago
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  • Taikhoom201042 minutes ago
    The problem is all these new labs don't have any competitive advanatge amongst each other, talent can only take one so far, though Jeff is a legend no doubt.

    Models are commodities the applications eg. BaseTen, OpenRouter should capture the value.

    https://taikhooms.substack.com/p/why-openrouter-can-be-the-n...

    • compiler-guy35 minutes ago
      The company is developing an application, or a class of applications. Not a new model.
    • make322 minutes ago
      I think Google's branding was starting to be too poor in AI to get top talent, they needed the refresh
    • malux8530 minutes ago
      Model routers - send all of your data through a third party who totally swears not to peek at it.

      If youre doing anything worthwhile (advanced research, classified work, high value industrial research, health data, or anything high value) then sending your data through a third party like that is insane.

      • adfm12 minutes ago
        FHE
  • Johnny_Bonkan hour ago
    For sure made with Claude code for front end, but I’m excited to see where they go
  • Noe209723 minutes ago
    This looks like a realization of "benevolent self conscious AIs agreeing to cooperate with mankind to do great stuff". Often in these tales, there is a hidden cost to it: the AI has its own agenda, or does crazy experiments with humans mind/brain. I'm wondering what shape will take that plot twist in reality :)
  • melodyogonnaan hour ago
    Oh wow, that's a blow to Google, what's with the talent scarcity in ML. Though if this goes anywhere Google will likely buy them back.
    • FailMore43 minutes ago
      Google down $160Bn so far since the leaving announcements. Those are some valuable people!
      • IAmGraydon36 minutes ago
        Google is literally at the same stock price it was on Monday. This is a normal daily fluctuation for them.
    • jfrbfbreudhan hour ago
      Google is backing it.
    • 43 minutes ago
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  • swalsh35 minutes ago
    By the middle of the 2030's the world we live in will be unrecognizable.
    • kingofthehill9832 minutes ago
      I agree, for better or for worse.

      If I had to bet my money, it would be on "for worse".

    • dude25071124 minutes ago
      It will not be owned by top 1%?
      • swalsh21 minutes ago
        That seems to be the one unchanged variable of time.
  • flakinessan hour ago
    > we have pioneered massive scale computing and led the creation of critical infrastructure, products, and foundational AI advances that the world relies on, including multiple generations of Google Search, Google Ads, Google News, Google Translate, Google File System, MapReduce, BigTable, Spanner, TensorFlow, Pathways, TPUs, AlphaChip, AlphaStar, AlphaCode, AlphaFold, Gemini, model distillation, mixture-of-experts model architectures, word2vec, sequence-to-sequence models, chain of thought reasoning, neural architecture search, and multiple generations of Large Language Models (LLMs) among others.

    holy shit. I've known this, but...

  • syntaxing42 minutes ago
    This reminds me of Three body problem and how the scientist discovered the high strength wire was through quick physical experiments and use them as input to an AI model to determine if it works.
  • deerstalker41 minutes ago
    National Labs in the US have been doing this for a while now. I feel like the private sector will take the lead soon.
    • pphysch17 minutes ago
      Why? Science is wildly unprofitable on the scale of an individual private firm.
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  • 1970-01-01an hour ago
    I'm skeptical of any Engineering loop that doesn't include reality (as in touch grass) feedback. Pure logic and reasoning is the domain of Maths and Science (philosophy). Surely it will work, but it will not "be able to solve any learning loop".
  • sidcool40 minutes ago
    I am available for hire.
  • numbers_guy30 minutes ago
    When they say experiments, do they mean using physics simulators?
    • danielmarkbruce5 minutes ago
      in AI/ML, no. They are just going to automate AI/ML research to start with. Totally doable.

      For some of the other things, undoubtably yes.

  • ChrisArchitect37 minutes ago
    Related:

    Jeff Dean leaving Alphabet

    https://news.ycombinator.com/item?id=49184746

  • searine37 minutes ago
    Computation is not the hard part of discovery.
  • bezko41 minutes ago
    So Ralph Wiggum in a suit?
  • mosfetsan hour ago
    Is this a joke? Site is not loading for me.
  • yddryhry34 minutes ago
    you people worship money and money only and cannot see vaporware because of it.
    • daishi5517 minutes ago
      Yeah what these guys are mainly known for is vaporware

      > we have pioneered massive scale computing and led the creation of critical infrastructure, products, and foundational AI advances that the world relies on, including multiple generations of Google Search, Google Ads, Google News, Google Translate, Google File System, MapReduce, BigTable, Spanner, TensorFlow, Pathways, TPUs, AlphaChip, AlphaStar, AlphaCode, AlphaFold, Gemini, model distillation, mixture-of-experts model architectures, word2vec, sequence-to-sequence models, chain of thought reasoning, neural architecture search, and multiple generations of Large Language Models (LLMs) among others.