They apparently settled on the the sequences for the original covid vacs in a weekend. Going from that design to billions of doses is one of the hardest things to do, but once done, will persist. And it is ready to be deployed for the next hundred applications that we find for this.
Flu vaccines is an obvious application, since the prior egg-based manufacturing required about six months lead time and millions of eggs, but nobody wanted to invest in anything better.
Seems to have been a legitimate, very rare, side effect
https://www.flinders.edu.au/research/articles/covid-vaccine-...
You don't have to care about the people who aren't interested in science. Sure, you have to protect immunocompromised people from those people, and we can do that.
I can absolutely empathize though. It really is fucked up to experience it in the extreme. Usually the trade-offs are much more minor or have a big time delay or are more abstract.
It's about swaying investors and regulators. And yeah, we need to make sure we excise our regulators of crazy people, but that's cyclic. And next cycle, we'll get vaccines for a lot more.
You cannot reason a person out of a position they did not reason themself into in the first place.
Grifters like RFK Jr and the supplement charlatans are cashing in on the lies they perpetuate.
And intuitively it makes sense we’re talking about groups of people who are skeptical of main stream institutional health recommendations but trust specific personal sources for medical advice.
I’m vibing but it feels like there is a pretty clear intersection of peptides and the fringe science health community no?
As many of us said at the time, the mandates weren't worth the destruction of public trust, especially because the vaccine wasn't even sterilizing.
The next time there's a crisis, resist the urge to use the government to achieve outcomes by brute force. It doesn't work and has generational adverse consequences.
Proceeds to raw dog a bunch of “research chemicals” cause some roided up bro talked about it on a podcast…
https://m.youtube.com/watch?v=U7gbFMWZWlo
They’re not vaccines though.
This book pushes Ivermectin and Hydroxychloroquine as "miracle cures", thanks to that idea my relatives also have a stockpile of both.
If you mean lots of people cite it, well, that's the grift. It's lies sold to people desperate for validation of their conspiracy theories.
If you mean that it's a book based on good citations, well, hah, very untrue.
Tailored vaccines for things like cancer are a game changer.
I live in hope of a semi-universal flu+related vaccine.
I live in fear of the measles induced "immune amnesia" effect.
Even during the pandemic response it was eventually acknowledged that early claims of vaccines preventing infection or even spread weren't supported by the trials. Trials were only done to study how many participants sought medical attention for symptomatic infection and had no data related to spread or asymptomatic carriers (or even those who just didn't seek care, though hopefully that was negligible).
The overview of this article seems to lean heavily on existing studies, modeling, and observational studies. Modeling and observational studies can only indicate correlation rather than causation, and I'm not aware of controlled studies for mRNA vaccines that tested for protection against infection or spread.
To the very best of my knowledge this is just misinformation. If you have a citation here, please provide it.
I can find you links, though it will be directly to the original studies done for the covid vaccines. The studies were well written and clearly called out their methodology. The problem was with how the studies were interpreted and explained to the public, not with the studies themselves.
The studies only ran for 3-4 weeks each, at which point they were unblinded. Though they did continue tracking reported adverse events for a while if I'm not mistaken, the study was no longer blind or controlled at that point though so I don't put any weight behind that data (I'm sure there's plenty that disagree with me disregarding data collected after the unblinding).
Seriously though, I am very pro-vax, but the fact that studies like these come out now is just confirmation that people had the right to doubt the safety of mRNA back then. Many people shamed others for being anti vax but everyone has the right to be careful.
I’m also pro-vax, so I don’t think it is correct to equate ignoring the preponderance of current evidence (in 2021 or 2026) for vaccine protection as being careful. That just seems the logical fallacy sold by “vax hesitant” and social media influencers to make people feel smart to ignore statistics and “make their own choice based on intuition”
reminder to the myocarditis-maxxies, the actual virus causes that too and the 2020-2021 variants caused it worse
if we were all going to drop dead (I think 2 years ago now, I’m waaaaiting!) for whatever the vaccine did, it would apply to a broader population due to covid exposure
Do you know if the vaccine prevented the virus-induced myocarditis? Cause the vaccine didn't do much to stop people from getting covid, multiple times even.
So many people frame this as either/or, you either had the risk of covid induced myocarditis or you had the (supposed) lesser risk of myocarditis from the vaccine. But if you got the vaccine (x times) and then covid (y times), isn't your risk roughly x + y?
none of those were goals of the vaccine, so its a fruitless exercise to build on top of
they communicated poorly at all levels the one time society needed them to communicate effectively, and lost the public trust
The goal was to reduce the spread overall, lessen the symptoms for individuals, have your own body fight it faster instead of becoming a factory for it, de-risking cytokine storms
Channeling Monty Python:
... I got better
This sounds a bit like providing evidence for global warming, gun control or evolution. The "skeptics" just want to remain ignorant. No amount of evidence will change them.
The silver lining about vaccine skeptics, though, is the Herman Cain award[1]. What this means is that conservatives die more than liberals from preventable diseases [2].
Say what you will about the Covid vaccine or Kennedy’s specific motivations (which I disagree with), but choosing to cut government funding for development of wildly profitable pharmaceutical products is a reasonable choice.
We don’t generally fund Merck’s R&D with federal money. You’ll note the following critical detail from the article:
> That will impact 22 projects being led by major pharmaceutical companies, including Pfizer and Moderna, for vaccines against bird flu and other viruses, HHS said.
We’ve gone so far round the bend with partisanship that straight-up corporate welfare has become a left-wing cause.
for the curious:
https://www.usaspending.gov/search?hash=5ec35bf87ec1fd63d28d...
Remember when everyone was contributing spare dimes to fund a vaccine?
If the government never funded another study for vaccines, ever, pharma companies would continue to pump them out.
Also, for the record: very few (no?) vaccines are “mandated” by the federal government. Recommendations are made, and state and local governments do this, mainly through school districts.
Various agencies and the military will, of course, mandate things for their own staff.
The game to compensate for that is to be to convince gullible investors that your commercially viable fusion plant, or quantum computer, or unrealistic space ambitions are just 5 years away! Invest now or miss out!
The line between research and scamming in an ultracapitalist economy becomes very blurry.
Trump 1 was a very different administration.
And Trump himself has publicly backed off what was probably his one major achievement after receiving pushback from his supporters.
Trump one had a sane (terrible, but sane) cabinet that largely controlled his wilder impulses.
This time he went for loyalty above all else.
This is absurdly revisionist. The first administration’s cabinet/staff was a reality show and a merry go round of people like Anthony Scaramucci and Ryan Zinke. If anything “controlled” it, it was just the chaos of incompetence.
As far as loyalty goes, I suppose it’s worth reminding you that Kennedy was a Democrat, who ran in the Democratic presidential primary, and routinely criticized Trump.
1: https://apnews.com/article/maha-glyphosate-rfk-kennedy-trump...
Kennedy was a Democrat as a spoiler.
Here's what we know: In 2014, Obama administration halted the so called "gain of function" research because of risk of laboratory accidents. In 2017, the Trump administration restarted this dangerous research. See links below.
https://www.nytimes.com/2014/10/18/us/white-house-to-cut-fun...
Excerpt: [Obama administration] White House announced Friday that it would temporarily halt all new funding for experiments that seek to study certain infectious agents by making them more dangerous. The White House said the moratorium decision had been made “following recent biosafety incidents at federal research facilities.”
https://www.nytimes.com/2017/12/19/health/lethal-viruses-nih...
Excerpt: [Trump administration] on Tuesday ended a moratorium imposed three years ago on funding research that alters germs to make them more lethal. Critics say these researchers risk creating a monster germ that could escape the lab and seed a pandemic.
So, Trump restarted the dangerous research that Obama had shut down. You may be thinking, what does that have to do with Covid? Covid started in Wuhan, China, right?
It turns out that the Trump administration, through the National Institutes of Health (NIH), provided funding to the EcoHealth Alliance, an American non-profit organization focused on studying emerging diseases. The EcoHealth Alliance, in turn, provided funding to the Wuhan Institute of Virology in China for researching bat coronaviruses. The rest is history.
And then Trump also disbanded the pandemic preparedness team in 2018 just in time for the pandemic. See link below.
https://www.washingtonpost.com/outlook/nsc-pandemic-office-t...
Most left-wing critics are still struggling with admitting that Anthony Fauci really did provide funding to EcoHealth, despite ample documentation.
For the record, I don’t care who gets blamed. I just think it’s a hilarious twist of partisan rhetoric.
The closest to “untested drug matter” that existed was the antibody cocktail that might have kept Trump alive.
The mRNA approach already had years of work prior to COVID, and was already reviewed for safety.
It's worth highlghting the importance of years of basic science-research and testing, all little pieces which were mostly there when we finally needed them, work that was always under-threat from people saying "what use is this, why would we ever need that?" (For which the pandemic is an implicit answe the pandemic answered: "Stuff like this!")
Among many of those collective small contributions that create a practical and effective outcome, one example of work thankfully done in advance:
> But the thing is, our vaccine is only generating the spikes itself, and we’re not mounting them on any kind of virus body. It turns out that, unmodified, freestanding Spike proteins collapse into a different structure. If injected as a vaccine, this would indeed cause our bodies to develop immunity.. but only against the collapsed spike protein. And the real SARS-CoV-2 shows up with the spiky Spike. The vaccine would not work very well in that case.
> In 2017 it was described how putting a double Proline substitution in just the right place would make the SARS-CoV-1 and MERS S proteins take up their ‘pre-fusion’ configuration, even without being part of the whole virus. This works because Proline is a very rigid amino acid. It acts as a kind of splint, stabilising the protein in the state we need to show to the immune system. The people that discovered this should be walking around high-fiving themselves incessantly. Unbearable amounts of smugness should be emanating from them. And it would all be well deserved.
[0] https://berthub.eu/articles/posts/reverse-engineering-source...
A different roll of the mutation dice might have made a sars that spread easily. That would have thinned out the middle aged folks.
/S
But I'm not quite sure how that's relevant to the article...
We're way beyond lysenko. China has no intellectual or political baggage in vaccine theory or bio engineering.
But better late than never I suppose.