we know people can exist and be productive in orbit for extended periods.

we know people can make it to the moon remain for a time, and perform tasks, then return.

energy generation, probably has to be nuclear, structures require low G engineering.

we know "robots" can make it to mars and function for extended periods. very probably, there are locations that provide apparent resources required for extended human occupancy, and feasibility of development must be established. energy generation may be wind turbine, or some type of triboelectric harvesting of electric discharges.

in both cases, its probably a good plan to pre emptively develop chattels of occupation. the idea of constructing self sufficient fabrication and launch facilities on the moon should be seriously examined.