the experiment on "giving up" is pretty cool:
>All the while, the researchers monitored neurons and astrocytes in the zebra fish’s brain using advanced whole-brain imaging techniques. As the fish fruitlessly fought the current, neurons that release norepinephrine fired; in response, calcium built up in astrocytes. The buildup paralleled the number of attempts the fish made to fight the current, as if the astrocytes were keeping track — until at some point they issued a stop signal, and the zebra fish gave up. When Ahrens’ team disabled the astrocytes using a laser, the fish never stopped swimming. And if the astrocytes were artificially activated, the fish stopped right away.