8 pointsby mhb2 days ago3 comments
  • robocat2 days ago

      But for me, when I drink alcohol, I get high, like energized. For some people, there's a sedating effect. But for me it was very energetic, almost like doing a little bit of, having a little bit of caffeine. I didn't drink to chill out. I drank to get ramped up.
    
      Naltrexone dulls that. There are various different ways to prescribe it, but the Sinclair method, which is what I did, it's very specific.
    
      You take this drug naltrexone [then you wait at least an hour], which is how long it takes to metabolize and then you drink as normally. And when you do, and this doesn't work for --
    
    
      And this is a really key part of the Sinclair Method. You only take naltrexone in anticipation of drinking. So if you're not going to drink, you do not take naltrexone. And so on alcohol free days, that leaves your opioid receptors, which are integral to this endorphin dump, it leaves them open, unblocked.
    
      And you try to fill your days with things that will create a natural high, this natural endorphin rush. And this is a way of basically retraining your brain to not expect pleasure from alcohol and to expect pleasure from other things.
  • LarsKrimia day ago
    Very interesting. She basically described my situation 100%. Sounds like I'll be talking to my doc ASAP

    The interesting part is that abstinence might work for some but without removing the pleasure association it is doomed for some that are guaranteed to relapse

  • konaraddi2 days ago
    The title is misleading imo, the tldr is using the Sinclair method to retrain the brain to associate pleasure with other desired activities but the discussion is interesting nonetheless.

    I think this falls within the more broad category of “elimination via substitution” techniques in breaking personal patterns.

    • LarsKrimia day ago
      People who are not addicted must feel joy somehow. Seasoned alcoholics are not unaware that the effects are messing with their pleasure centres

      To me it sounds less like substitution and more of a recalibration to normal levels. Where the brain learns that when it wants to have fun alcohol isn't the first thing it reaches out for