Prayer would just do nothing.
That might be a little harsh. I would at least compare it to a placebo. Chants and prayers can help keep ones hand in the box for the Reverend Mother. [1]
[1] - https://www.youtube.com/watch?v=RooSqqn1FjA [video][fear is the mind killer]
However, in my search I also found studies that showed prayer to be effective.